免疫的分子农业:植物生产疫苗的当前进展和未来前景
Dang-Khoa Vo1, Kieu The Loan Trinh2
1College of Pharmacy, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea.
Vaccines
|February 26, 2025
概括
分子农业使用植物生产疫苗和治疗药物,提供了可扩展和具有成本效益的方法. 进步提高了效率,但产量,净化和监管方面的挑战仍然需要更广泛的采用.
科学领域:
- 生物技术是生物技术.
- 分子生物学分子生物学
- 植物科学 植物科学
背景情况:
- 分子农业利用植物作为生物反应器,用于可持续生产生物制品.
- 与传统方法相比,基于植物的系统提供了可扩展性,成本效益和减少污染风险.
研究的目的:
- 审查目前植物性疫苗开发的现状和进展.
- 讨论生物制药分子农业的操作机制,应用和未来趋势.
主要方法:
- 关于植物表达系统,基因编辑和传递技术的最新文献的审查.
- 分析分子农业的成功应用,挑战和监管方面.
主要成果:
- 基于植物的平台已经在生产疫苗 (例如,COVID-19的Covifenz) 和治疗蛋白质方面取得了成功.
- 基因编辑和传递系统的进步提高了效率.
- 可食用疫苗为资源有限的环境提供了新的输送解决方案.
结论:
- 分子农业是可访问和具有成本效益的疫苗和生物制药生产的有希望的平台.
- 解决产量,净化和监管方面的挑战对于未来的发展至关重要.
- 该领域在传染病预防,个性化医疗和更广泛的生物制药应用方面具有重大潜力.
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