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Updated: May 25, 2025

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
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SARS-CoV-2 通过尖端葡萄糖蛋白和细胞因子失调破坏骨质细胞分化

Rosa Nicole Freiberger1, Cynthia Alicia Marcela López1, Patricio Jarmoluk1

  • 1Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Laboratorio de Inmunopatología Viral, Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Universidad de Buenos Aires (UBA), Buenos Aires 1121, Argentina.

Viruses
|February 26, 2025
PubMed
概括

包括Omicron在内的SARS-CoV-2通过抑制骨质母细胞分化来损害骨形成. 该病毒破坏骨质稳定,促进骨质再吸收,其作用由尖端糖蛋白介导.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.骨头 骨头 骨头 骨头骨质母细胞 (osteoblasts) 是一个骨质细胞.

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