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Updated: May 25, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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一个多基因的葡萄皮质激素暴露评分和与HPA轴相关的DNA甲基化与妊娠性表观遗传衰老有关

Allison A Appleton1

  • 1Department of Epidemiology and Biostatistics, University at Albany College of Integrated Health Sciences, Rensselaer, NY, USA.

Epigenetics
|February 26, 2025
PubMed
概括

通过DNA甲基化测量,产前暴露于葡萄皮质激素调节与减缓妊娠表观遗传衰老 (GEA) 有关. 这种表观遗传衰老模式可能表明新生儿的风险,有些影响在性别之间存在差异.

关键词:
妊娠表观遗传年龄偏差 妊娠表观遗传年龄偏差在HPA轴的DNA甲基化过程中健康和疾病的发育起源.多基因基因的葡萄糖皮质激素暴露得分.

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