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Updated: Jul 20, 2026

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通过SCD1下调的增强脂肪酸氧化促进心脏重编程

Zhenhua Jia1, Lilin Xiang2, Zhangyi Yu1

  • 1Department of Cardiology, Zhongnan Hospital of Wuhan University, Medical Research Institute, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan 430071, China; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.

Molecular therapy : the journal of the American Society of Gene Therapy
|February 26, 2025
PubMed
概括

脂肪酸氧化 (FAO) 对于将纤维细胞转化为诱导心肌细胞 (iCMs) 至关重要. 抑制stearoyl-coenzyme A脱酶1 (SCD1) 增强了这种心脏重编程过程.

关键词:
直接重新编程是直接的重编程.心脏再生心脏的再生代谢重编程是指代谢重编程.

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