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儿童发病的1型糖尿病成年人的执行功能缺陷:来自威斯康星州卡片排序性能测试的证据

Jing He^1,2,3, Wenjing Zou⁴, Hongyu Du^2,5

¹Department of Psychology, Hunan First Normal University, Changsha, Hunan, China.

Journal of diabetes investigation

|February 26, 2025

概括

1型糖尿病 (T1DM) 与执行功能 (EF) 障碍有关. 儿童发病的T1DM显示出比成人发病的T1DM更大的EF缺陷,这表明需要针对年龄的干预措施.

科学领域:

神经科学是一个神经科学.
内分泌学在内分泌学.
心理学心理学心理学

背景情况:

执行功能 (EF) 对于管理1型糖尿病 (T1DM) 自理至关重要.
以前的研究还没有完全阐明T1DM患者和健康对照人群之间的EF差异,也没有完全阐明T1DM发病组之间的EF差异.

研究的目的:

将T1DM患者的EF与健康对照 (HC) 进行比较.
调查儿童发病和成人发病T1DM之间的EF变化.
为了确定与T1DM的EF赤字相关的因素.

主要方法:

利用威斯康星州卡片排序测试 (WCST) 评估94名儿童T1DM,110名成年T1DM和100名HC参与者的EF.
进行智商评估的WAIS的中文版本和情绪评估的BDI-II.
在分析中控制了糖尿病持续时间和严重低血糖病史.

主要成果:

儿童发病和成人发病的T1DM组在WCST上表现较差,与HC相比.
儿童T1DM患者的总,坚持性和非坚持性错误明显高于成人T1DM患者,即使在控制糖尿病持续时间后.
在儿童发病的T1DM中,与T1DM持续时间相关的坚持性错误和非坚持性错误受到严重低血糖病史的影响.

结论:

1型糖尿病与执行功能障碍有关.
儿童发病和成人发病的T1DM之间存在显著的EF差异,早期发病与较大的缺陷有关.
临床注意力应集中在识别和解决T1DM患者的EF缺陷,以适应他们发病年龄.

关键词:

童年开始的T1DM 执行职能执行职能执行职能第1型糖尿病是什么?

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