甲状腺功能障碍的特征在患有心房动的患者中
A Abbasova1, V Mirzazade1, I Mustafayev1
1Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev, Department of Therapy, Baku, Azerbaijan.
Georgian medical news
|February 26, 2025
概括
甲状腺功能障碍,特别是甲状腺功能低下症,在心房动 (AF) 患者中很常见,并可能使AF症状恶化. 早期甲状腺查对于有效的AF管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 心房动 (AF) 是一种常见的心律失常.
- 甲状腺功能障碍越来越被认为是一种影响心血管健康的潜在并发症.
研究的目的:
- 为了调查甲状腺功能障碍在心房动患者的患病率和临床意义.
- 为了确定甲状腺疾病对AF严重程度,类型,形式和持续时间的影响.
主要方法:
- 通过临床评估,心电图,心声学,甲状腺超声波和甲状腺激素测试 (TSH,自由T3,自由T4,抗TPO) 评估了134名AF患者.
- 根据甲状腺功能,结构和自身免疫状况对患者进行分类.
主要成果:
- 38.1%的AF患者表现出甲状腺功能障碍 (甲状腺功能低下,甲状腺功能过高或伪甲状腺功能障碍).
- 甲状腺功能低下与更严重的AF症状相关 (EHRA类IV),但没有显著改变AF类型,形式或持续时间.
- 甲状腺功能障碍症对AF特征没有显著影响,但趋向于增加症状严重程度 (EHRA III-IV).
- 伪甲状腺功能障碍症是并发症的次要症状,需要仔细考虑,以避免误诊和不适当的治疗.
结论:
- 甲状腺功能障碍,特别是甲状腺功能低下,可能会加剧AF症状的严重程度.
- 建议对所有AF患者进行全面的甲状腺评估,以有效地识别和管理甲状腺疾病.
- 区分真正的甲状腺功能障碍与伪甲状腺功能障碍对于适当的患者管理至关重要.
相关概念视频
01:28Disturbances in Heart Rhythm
860
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
860
01:12Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
886
Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium channels or enhancing inward currents from sodium channels. However, these drugs have a unique property of "reverse use-dependence," which is most pronounced at slower heart rates and can lead to torsades de pointes—a specific type of arrhythmia. However, it is essential to note that excessive QT interval prolongation—a measure of...
886
01:28Mechanism of Cardiac Arrhythmias
872
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
872
01:16ECG Interpretation of Arrhythmias I: Sinus Arrhythmias
164
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
164
01:20Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
756
Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in calcium-dependent tissues like the SA and AV nodes. These drugs manage reentrant supraventricular tachycardia (SVT) and reduce ventricular rate in atrial flutter/fibrillation.
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
756
01:24Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
700
Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in intracellular calcium ion influx and pacemaker currents, which may cause arrhythmias. Catecholamines like adrenaline also demonstrate β2-adrenoceptor-mediated hypokalemia, impacting cardiac action potential and disrupting the normal cardiac rhythm. Class II antiarrhythmic drugs are β-adrenoceptor antagonists or β-blockers, which...
700