抗生素使用可以在跨口内镜甲状腺切除术期间降级:基于细菌培养的研究
Bingbing Wu1,2, Xiao Chen1, Junwei Huang1
1Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ear, nose, & throat journal
|February 26, 2025
概括
这项关于横口内镜甲状腺切除术前体方法 (TOETVA) 的研究发现,在手术后停止常规抗生素并不会增加感染风险. 在甲状腺切除术患者中,适当的排水是安全降低抗生素的关键.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 最少侵入性的手术
背景情况:
- 透口内镜甲状腺切除术前庭治疗方法 (TOETVA) 是甲状腺手术的一种微创手术.
- 在TOETVA手术期间使用抗生素的必要性仍在调查中.
- 优化抗生素协议可以降低医疗保健成本和抗菌素耐药性.
研究的目的:
- 评估在TOETVA之后减少或消除抗生素使用的可行性.
- 为了比较干净与干净受污染的手术场所的感染率和细菌殖民.
- 在TOETVA中评估抗生素给药对术后结果的影响.
主要方法:
- 针对T1差异化甲状腺癌或良性肠 (2022-2024) 接受TOETVA的患者的回顾性分析.
- 清洁和清洁污染切口组之间的感染率,排水液中的细菌培养和抗生素使用的比较.
- 基于经外科手术期间使用抗生素的结果分析.
主要成果:
- 没有观察到术后感染或延迟愈合.
- 在干净和干净污染的切口之间,感染率或细菌培养没有显著的差异.
- 接受抗生素和不接受抗生素的患者之间的感染率没有显著差异.
- 与干净的切口相比,在干净受污染的切口中,致病细菌的流行率更高.
结论:
- 在TOETVA中,经过适当的排水,外科手术期间的抗生素使用可能会减少或消除.
- 在手术腔中存在细菌并不一定会导致感染.
- 尽量减少TOETVA中的抗生素暴露是安全的,不会增加感染率.
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