在儿童中,经过透管心室隔膜缺陷关闭后,左心室尺寸迅速正常化
Hui Yuan1, Wenjing Zhu2, Jianli Lv1
1Department of Pediatric Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, China.
Heliyon
|February 26, 2025
概括
穿透管心室隔膜缺陷 (VSD) 关闭迅速使儿童的左心室尺寸正常化. 诸如年龄和VSD大小等因素影响了这种改善,支持了程序.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 干预心脏病学 干预心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
背景情况:
- 左心室 (LV) 扩张在患有心室隔膜缺陷 (VSD) 的儿童中很常见.
- 通过导管VSD关闭是一种新兴的治疗选择.
研究的目的:
- 在儿科患者中通过导管VSD关闭后评估LV维度变化.
- 为了确定影响LV维度规范化后期程序的因素.
主要方法:
- 对124名患有手术前LVZ分数≥2且接受过导管VSD关闭的儿童进行了回顾性研究.
- 在手术后的1,3,6和12个月内对LV终端透气直径 (LVEDD) Z-score进行心声评估.
- 二元逻辑回归分析以确定LV维度正常化的预测因素.
主要成果:
- 成功关闭透导管VSD导致LVEDD Z-score随着时间的推移显著下降.
- 87.1%的患者在术后1个月内实现了LVEDD Z-score正常化.
- 年轻的年龄和较小的VSD大小与1个月后更快的LVEDD Z-score正常化有关.
结论:
- 通过导管VSD关闭有效地使儿童的LV维度正常化,在第一个月内得到了快速改善.
- 年龄和VSD大小是影响LV维度恢复率的关键因素.
- 该程序是对儿科患者血液动力学显著的VSD的可行的治疗方法.
相关概念视频
01:16Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
01:27Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
01:20Mitral Regurgitation I: Introduction
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
01:15Aortic Regurgitation I: Introduction
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...