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炎症性肠道疾病中的牙周炎:患者和牙水平的元分析
Giusy Rita Maria La Rosa1, Alejandro Ismael Lorenzo-Pouso2, Vito Carlo Alberto Caponio3
1Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy.
Frontiers in dental medicine
|February 26, 2025
概括
在炎症性肠道疾病 (IBD) 患者中,性牙周炎 (AP) 更常见. 这次审查发现IBD患者中AP的患病率较高,这表明这些疾病之间存在潜在联系.
科学领域:
- 口腔医学是指口腔医学.
- 胃肠病学 胃肠病学
- 系统性审查和元分析
背景情况:
- 牙周周炎 (AP) 是一种与牙髓病相关的牙周组织炎症.
- 新出现的证据表明,口腔和胃肠道健康之间存在联系.
- AP和炎症性肠道疾病 (IBD) 之间的关系尚不清楚.
研究的目的:
- 系统地审查和分析被诊断为IBD的患者中AP的流行率.
- 评估AP和IBD之间的潜在关联.
- 评估有关AP-IBD关系的证据质量.
主要方法:
- 在Embase,PubMed,Scopus和Web of Science数据库中进行全面的文献搜索.
- 包括关注IBD患者AP的观察性和实验性临床研究.
- 使用乔安娜·布里格斯研究所工具和GRADE方法对证据质量进行偏见风险评估.
主要成果:
- 包括5项涉及657名受试者和7142颗牙的研究.
- 总体AP患病率在患者水平为58%,在牙水平为7%.
- 与健康对照人群相比,IBD受试者中AP的患病率明显高 (OR 1.57患者水平,OR 1.91牙水平),证据质量低至非常低.
结论:
- 顶端牙周炎和炎症性肠道疾病之间存在合理的关联.
- 目前的证据质量低到非常低,需要进一步研究.
- 建议进行纵向和实验性研究,以阐明病因因素并加强证据基础.
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