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老年人营养风险指数和老年人膀过活之间的关联:一个横截面研究
Wei Zheng1,2, Chuanzan Zhou3, Jia Miao4
1Emergency and Critical Care Center, Department of Emergency Medicine, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Frontiers in nutrition
|February 26, 2025
概括
低老年营养风险指数 (GNRI) 表示的营养不良与老年人膀过活 (OAB) 有关. 较低的GNRI预测OAB风险,炎症起着关键作用.
科学领域:
- 老年医学 老年医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 营养科学 营养科学
背景情况:
- 过度活性膀 (OAB) 的患病率在老年人中正在上升.
- 营养不良越来越被认为是影响尿道系统的一个因素.
- 关于老年人营养状况和OAB之间的具体联系的研究有限.
研究的目的:
- 为了研究由老年营养风险指数 (GNRI) 评估的营养状况与老年人过度活动膀 (OAB) 的患病率之间的联系.
- 探索GNRI对OAB的预测价值,并了解炎症反应和认知功能中介作用.
主要方法:
- 来自国家健康和营养检查调查 (2005-2018) 的17161名老年人的分析.
- 使用过度活性膀症状评分 (OABSS) 评估OAB症状.
- 采用了多因素后勤回归,受限立方线线图,子组分析,ROC曲线和调解分析.
主要成果:
- 老年营养风险指数 (GNRI) 在过度活性膀 (OAB) 组明显低于非OAB组.
- 确定GNRI是老年人OAB的显著独立预测因子,显示非线性反向相关性.
- 与单独的血清白蛋白或体重指数 (BMI) 相比,GNRI对OAB风险的预测能力更强,而炎症则调解了这种关系.
结论:
- 老年营养风险指数 (GNRI) 是老年人膀过活 (OAB) 的可靠预测指标,与OAB患病率呈现非线性反向关系.
- 炎症反应显著调解了GNRI和OAB发展之间的关联,突出了干预的潜在途径.
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