欧斯塔基管的气球扩张对于成年人的阻塞性欧斯塔基管功能障碍
Chloe Swords1,2, Matthew E Smith1,2, Anant Patel3
1Department of ENT Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
The Cochrane database of systematic reviews
|February 26, 2025
概括
气球尤斯塔基管整形 (BET) 可以改善阻塞性尤斯塔基管功能障碍的短期症状. 然而,对于BET的证据,
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗干预 医疗干预
- 临床试验 临床试验
背景情况:
- 欧斯塔基管功能障碍 (ETD) 涉及中耳压力失调,导致诸如中耳炎等疾病.
- 气球尤斯塔奇管道整形 (BET) 是阻塞性ETD的外科选择,但其疗效和安全性需要进一步评估.
研究的目的:
- 评估Eustachian管 (BET) 的气球扩张在阻塞性ETD的成年人中的有效性和安全性.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析.
- 在多个数据库中搜索了比较BET与非手术,无治疗或其他手术干预的试验.
- 包括9个RCT,684名参与者;使用GRADEpro.pro评估偏差风险和证据确定性.
主要成果:
- 低确定性证据表明,与非手术治疗相比,BET可能会减少ETD症状,长达三个月.
- 非常低的确定性证据表明,BET可能会在短期内客观地改善ETD.
- 对长期影响的证据和与其他手术的比较仍然非常不确定,研究往往具有偏见和不准确的高风险.
结论:
- 与非手术或假冒治疗相比,BET可能为阻塞性ETD提供短期症状缓解.
- 证据的确定性低至非常低,特别是在长期结果和安全方面.
- 需要进一步研究长期疗效和现实世界的不良事件发生率.
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