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Updated: May 25, 2025

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
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通过非致病性人类抗体对HLA-A*11:01结合的TCR封闭

Maryam Hamidinia1,2, Yue Gu1,2,3, Zheng Ser4

  • 1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Cellular and molecular life sciences : CMLS
|February 26, 2025
PubMed
概括

一些人类白细胞抗原 (HLA) 特定抗体可以通过阻断T细胞反应来保护移植器官,从而挑战所有此类抗体都会导致排斥的观点. 这一发现表明,在移植中对特定的HLA抗体有潜在的治疗应用.

关键词:
允许抗体使用.交叉连接质谱法 (XL-MS) 是一种质谱法.提供者特异性抗体 (DSA)人类抗体的人类抗体.移植 移植 移植 移植

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