烧伤损伤大小对心血管反应对在炎热环境下炼的影响
Zachary J McKenna1, Whitley C Atkins2, Elizabeth A Gideon1
1Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
European journal of applied physiology
|February 26, 2025
概括
患有大烧伤 (>40%的身体表面积) 的成年人由于温度调节受损,在炎热的运动中经历了更大的心血管应变. 这凸显了在烧伤幸存者中需要仔细的热应激管理的需要.
科学领域:
- 生理学 生理学 生理学
- 热调节 热调节 热调节
- 心血管反应的反应
- 烧伤伤害康复 烧伤伤害康复
背景情况:
- 热调节障碍在已治愈烧伤的成年人中得到了很好的认可.
- 这些损害可以导致暴露在热量中的热应变增加.
- 在高温运动期间对心血管反应的影响尚未完全理解.
研究的目的:
- 为了测试成年人愈合烧伤的假设,加剧了心血管对高温运动的反应.
- 为了比较不同烧伤表面积严重程度 (20-40%和>40%的TBSA) 和对照者的心血管反应.
主要方法:
- 研究包括已治愈烧伤的成年人 (20-40%的TBSA,>40%的TBSA) 和没有烧伤的对照.
- 参与者在炎热的环境 (39°C,40%RH) 中以固定代谢热量产生1小时的跑步机行走.
- 测量包括核心温度,心率,中风体积,血压和计算的心脏工作.
主要成果:
- 与对照组相比,患有>40%的TBSA烧伤的个体表现出明显更高的最终心率和心率压力产物.
- >40%的TBSA组与对照组在45分钟的运动后心脏分钟工作增加.
- 核心温度的增加在>40%的TBSA组中是最高的,尽管在统计学上并不显著 (p=.08).
结论:
- 经过充分治愈的大型烧伤 (>40% TBSA) 的烧伤幸存者在高温运动期间表现出心血管应变的增加.
- 这种人群的温度调节缺陷有助于增加生理压力.
- 研究结果强调了管理热应激在严重受伤的烧伤幸存者的重要性.
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