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Updated: May 25, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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激活STING可以改善T细胞参与的免疫疗法,用于治疗急性髓性白血病

Andreas Linder1,2, Daniel Nixdorf3,4, Niklas Kuhl1

  • 1Gene Center and Department of Biochemistry, Ludwig Maximilian University of Munich, Munich, Germany.

Blood
|February 26, 2025
PubMed
概括

将一种STING激动剂与一种向CD33的双特异抗体 (BsAb) 结合起来,显著提高了它对急性髓性白血病 (AML) 的有效性. 这种方法可以促进T细胞活动和AML细胞的杀死,为AML治疗提供了一个有前途的新策略.

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