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Updated: Jun 13, 2025

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一个第一类的JAK/ROCK抑制剂,罗瓦迪基替尼,用于抗胰岛素或依赖胰岛素的慢性GVHD

Yanmin M Zhao1,2,3, Yi Luo1,2,3, Jimin M Shi1,2,3

  • 1Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Blood
|February 26, 2025
PubMed
概括

罗瓦迪基尼布通过向炎症和纤维化,有效治疗慢性移植对宿主疾病 (cGVHD). 这项研究发现,它耐受性很好,反应率显著,减少了类固醇依赖,改善了患者的生活质量.

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