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Updated: May 25, 2025

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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登诺苏马布通过抑制SPP1和增强细胞毒性T细胞来增强抗瘤免疫力

Zezhuo Su1, Maximus Chun Fai Yeung1, Shan Han1

  • 1University of Hong Kong, Hong Kong, Hong Kong.

Cancer immunology research
|February 26, 2025
PubMed
概括

丹诺苏马布 (denosumab) 是一种RANK配体抑制剂,通过降低骨质素 (SPP1) 和增强细胞毒性T细胞来增强抗瘤免疫力. 这一发现为各种癌症中SPP1水平升高的患者提供了新的治疗潜力.

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