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相关概念视频

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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基于OCT的新 keratoconus 分类系统:对SS-OCT的门调整.

Nan-Ji Lu1, Frederik Raiskup, Lutz E Pillunat

  • 1From the Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China (Lu); Department of Ophthalmology, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany (Raiskup, Pillunat, Herber); National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China (Wang, Cui); State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China (Wang, Cui).

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概括

对于上皮质厚度,STEP形形形分级系统与扫描源OCT (SS-OCT) 显示出良好的性能,但需要调整层状形厚度的值. SS-OCT和SD-OCT之间的差异突出了临床实践的考虑因素.

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科学领域:

  • 眼科医生 眼科 眼科
  • 医疗成像医学成像
  • 生物医学工程 生物医学工程

背景情况:

  • 角膜 (KC) 是一种进展性角膜疾病,影响视力.
  • 准确的厚度测量对于KC诊断和管理至关重要.
  • 光学连贯断层扫描 (OCT) 技术,包括扫描源OCT (SS-OCT) 和光谱域OCT (SD-OCT),提供先进的成像功能.

研究的目的:

  • 为了评估使用SS-OCT的STEP形类分级系统的性能.
  • 为了比较SS-OCT和SD-OCT设备之间的厚度测量的准确性.
  • 评估SS-OCT衍生的STEP参数与已建立的角分级系统的一致性.

主要方法:

  • 一项追溯病例控制研究,涉及德国和中国的大学医院.
  • 分析了152个正常眼睛和314个KC眼睛的数据,使用旋转 Scheimpflug 断层扫描 (RSC,Pentacam) 和SS-OCT (ANTERION).
  • 使用Bland-Altman图和线性回归,比较SS-OCT与RSC ABC系统以及评估与SD-OCT (RTVue-XR) 的设备间一致性.

主要成果:

  • 在正常和KC眼中,STEP上皮质 (EP) 参数与RSC ABC系统有很好的一致性.
  • 在KC眼中,STEP流层最薄厚度 (ST) 参数与RSC"C"度量表达了较低的一致性,需要进行值调整.
  • 据SS-OCT估计的侧膜厚度值高于SD-OCT的估计,平均差异为23.18微米 (正常) 和20.91微米 (KC眼睛).

结论:

  • SS-OCT的STEP EP参数与RSC ABC系统的角评估非常一致.
  • 为了准确的临床应用,需要对SS-OCT的STEP ST进行调整.
  • 在SS-OCT和SD-OCT之间观察到的厚度测量差异需要仔细考虑未来的临床实践和管管理研究.