基于OCT的新 keratoconus 分类系统:对SS-OCT的门调整
Nan-Ji Lu1, Frederik Raiskup, Lutz E Pillunat
1From the Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China (Lu); Department of Ophthalmology, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany (Raiskup, Pillunat, Herber); National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China (Wang, Cui); State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China (Wang, Cui).
Journal of cataract and refractive surgery
|February 26, 2025
概括
对于上皮质厚度,STEP形形形分级系统与扫描源OCT (SS-OCT) 显示出良好的性能,但需要调整层状形厚度的值. SS-OCT和SD-OCT之间的差异突出了临床实践的考虑因素.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 角膜 (KC) 是一种进展性角膜疾病,影响视力.
- 准确的厚度测量对于KC诊断和管理至关重要.
- 光学连贯断层扫描 (OCT) 技术,包括扫描源OCT (SS-OCT) 和光谱域OCT (SD-OCT),提供先进的成像功能.
研究的目的:
- 为了评估使用SS-OCT的STEP形类分级系统的性能.
- 为了比较SS-OCT和SD-OCT设备之间的厚度测量的准确性.
- 评估SS-OCT衍生的STEP参数与已建立的角分级系统的一致性.
主要方法:
- 一项追溯病例控制研究,涉及德国和中国的大学医院.
- 分析了152个正常眼睛和314个KC眼睛的数据,使用旋转 Scheimpflug 断层扫描 (RSC,Pentacam) 和SS-OCT (ANTERION).
- 使用Bland-Altman图和线性回归,比较SS-OCT与RSC ABC系统以及评估与SD-OCT (RTVue-XR) 的设备间一致性.
主要成果:
- 在正常和KC眼中,STEP上皮质 (EP) 参数与RSC ABC系统有很好的一致性.
- 在KC眼中,STEP流层最薄厚度 (ST) 参数与RSC"C"度量表达了较低的一致性,需要进行值调整.
- 据SS-OCT估计的侧膜厚度值高于SD-OCT的估计,平均差异为23.18微米 (正常) 和20.91微米 (KC眼睛).
结论:
- SS-OCT的STEP EP参数与RSC ABC系统的角评估非常一致.
- 为了准确的临床应用,需要对SS-OCT的STEP ST进行调整.
- 在SS-OCT和SD-OCT之间观察到的厚度测量差异需要仔细考虑未来的临床实践和管管理研究.
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