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Rv2741通过通过IL-1α-MAPK轴调节巨细胞功能来促进菌根菌的生存

Xintong He1, Yonglin He1, Xichuan Deng2

  • 1Department of Pathogenic Biology, School of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.

ACS infectious diseases
|February 26, 2025
PubMed
概括

结核病 (TB) 涉及PE_PGRS蛋白质,如Rv2741,这有助于Mycobacterium结核病的生存. 这项研究表明Rv2741抑制宿主免疫反应,包括IL-1α分泌和MAPK信号,促进细菌毒性.

关键词:
结核病菌菌菌的结核病菌的结核病菌.没有,没有,没有,没有.在PE_PGRS家族中,Rv274141 这是一个很好的选择.灭症 (apoptosis) 是一种死亡的过程.

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