在接受过导管边缘到边缘修复的患者中评估老年营养风险指数
Kenichi Shibata1, Masanori Yamamoto2, Ai Kagase3
1Department of Rehabilitation, Nagoya Heart Center, Nagoya, Japan.
JACC. Advances
|February 26, 2025
概括
老年人营养风险指数 (GNRI) 预测了经过过导管边缘到边缘修复 (TEER) 进行 mitra regurgitation (MR) 的患者的死亡率. 较低的GNRI得分表明死亡风险更高,无论MR的原因如何.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 过导管边缘到边缘修复 (TEER) 是对额头回 (MR) 的关键治疗方法.
- 老年营养风险指数 (GNRI) 是评估老年人死亡风险的既定标志物.
研究的目的:
- 调查GNRI水平与不同额头回 (MR) 病因之间的关联.
- 确定GNRI对预测TEER患者临床结果的相关性.
主要方法:
- 分析了3,554名接受TEER治疗的日本MR患者的数据.
- 患者被分为四个GNRI组 (<82,82-92,92-98,>98) 的分层.
- 程序和临床结果的比较,包括通过考克斯回归的短期和长期全因死亡率.
主要成果:
- 观察到的GNRI中位数为92.3;在平均586.8天的随访期间发生了806例死亡.
- 最低的GNRI组 (<82) 呈现出最高的30天死亡率.
- 卡普兰-梅尔分析显示,GNRI组对整体队列,功能性MR和退行性MR (P < 0.001) 的预后明显更好.
- 与>98组相比,调整后的考克斯回归表明死亡风险逐步增加,GNRI得分下降.
结论:
- 不管病因,GNRI有效地预测了接受MRTEER的患者的短期和长期死亡率.
- TEER甚至在经历营养不良的腹患者中也表现出有效性.
- 进一步的研究是有必要的,以探索识别和管理这种患者群体的营养不良的好处.
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