HLA

David Göhring1, Maren Goeckenjan2, Inés Göhring3

  • 1Department of Gynecology and Obstetrics, TU Dresden, Fetscherstr. 74, 01307 Dresden, Germany; Kinderwunschpraxis Dres. Göhring, Hagellocher Weg 63, 72072 Tübingen, Germany.

概括

初级不孕症与人类白细胞抗原 (HLA) 的相似性有关. 经历不孕症的夫妇显示HLA相似性高于偶然预期的,特别是在HLA类2位点.

相关概念视频

Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
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Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
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