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Updated: May 25, 2025

A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases
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A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases

Published on: December 23, 2013

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在基因组维护中NEIL1的作用

Amanda K McCullough1, Irina G Minko2, Michael M Luzadder2

  • 1Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR 97239, United States; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, United States.

DNA repair
|February 26, 2025
PubMed
概括

类似NEI的DNA糖酶1 (NEIL1) 修复了DNA损伤,从而防止癌症. 在NEIL1中的遗传变异可能会增加因基因毒性暴露的人类疾病风险.

关键词:
基因切除修复 DNA 基因切除修复基因糖解酶/基基位溶解酶的DNA.肝癌是一种肝癌.代谢综合征是代谢综合征.遗传学保护 遗传学保护单核酸多态变体的单核酸变体

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