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Updated: May 25, 2025

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针对YTHDF1的纳米组件通过表观遗传学和细胞周期调节逆转瘤免疫逃避

Hongting Liu1, Xichu Zhang1, Fangchun Ding1

  • 1NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients, State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China.

Journal of controlled release : official journal of the Controlled Release Society
|February 26, 2025
PubMed
概括

这项研究引入了一种新的纳米组件,将铁化和YTHDF1siRNA结合起来,用于对抗癌症. 这种方法通过调节MHC-I并增强T细胞反应来恢复抗瘤免疫力,有效治疗乳腺癌并预防复发.

关键词:
细胞循环停止 细胞循环停止免疫调节是一种免疫调节.在 YTHDF1 的位置上.m(6) 一个调制器.siRNA的传递方式

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