对视网母细胞瘤进行动脉内化疗的导管复杂化
Craig Schreiber1,2, Gary Kocharian3,2, Natasha Kharas3
1Department of Neurological Surgery, Weill Cornell Medicine, New York, New York, USA cpq9005@med.cornell.edu.
Journal of neurointerventional surgery
|February 26, 2025
概括
对视网膜母细胞瘤 (Rb) 的动脉内化疗 (IAC) 在儿童中是安全的. 导管治疗的并发症率较低,特别是在使用较小的导管系统时,支持IAC作为可行的治疗选择.
科学领域:
- 眼科医生 眼科 眼科
- 儿科瘤学 儿科瘤学
- 干预性放射学 干预性放射学
背景情况:
- 动脉内化疗 (IAC) 是对视网膜母细胞瘤 (Rb) 的新兴治疗方法.
- 有限的数据存在于儿童患者IAC导管的安全性.
- 这项研究针对儿科Rb患者的非眼科,导管相关并发症.
研究的目的:
- 评估儿童视网膜母细胞瘤患者IAC导管治疗的安全性.
- 识别和分析非眼部,导管/手术相关的并发症.
- 为执行IAC的其他实践提供基础,并帮助预防并发症.
主要方法:
- 从2006年5月到2024年5月接受IAC治疗的儿科Rb患者的回顾性审查.
- 对非眼导管相关并发症的所有手术进行分析,包括入口,远部血管问题和心脏病发作.
- 对623名患者2281次血管接入事件和2681次远端导管术程序的综述.
主要成果:
- 总共发生了31种与 катетеризация相关的并发症 (总体为1.1%).
- 进入大腿动脉的并发症:7 (0.3%).
- 远端血管损伤:24 (0.9%),包括2次无症状脑梗塞 (0.07%).
结论:
- 在儿科视网膜母细胞瘤患者群体中,用于IAC的导管治疗是安全的.
- 一个趋势表明,较小的导管系统会导致更少的并发症.
- IAC是幼儿视网膜母细胞瘤的安全和可行的治疗方法.
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