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Updated: Jun 14, 2025

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TGT通过在Anticodon循环中形成亚基位址来损害其基质tRNA

Kevin Kopietz1, Kasturi Raorane2, Wei Guo3

  • 1Johannes Gutenberg-University Mainz, Institute of Pharmacy and Biomedical Sciences, Staudingerweg 5, 55128 Mainz, Germany.

Journal of molecular biology
|February 26, 2025
PubMed
概括

tRNA-瓜氨酸转糖酶 (TGT) 酶不小心在tRNA中产生RNA基底位 (rAP),导致受损,非功能性RNA. 这种RNA损伤在压力条件下被放大,并在各种小鼠组织中观察到.

关键词:
RNA基底部部位 (rAP) 是RNA基底部部位.造成RNA损伤的RNA损伤RNA-蛋白质共价添加物RNA-蛋白质共价添加物催化机制是一种催化机制.tRNA-瓜氨酸转糖酶 (TGT) 是一种

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