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Updated: May 25, 2025

Zebrafish Model of Neuroblastoma Metastasis
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8q24衍生的ZNF252P通过驱动相分离促进瘤发生,以激活c-Myc介导的反循环

Tianyu Qu1, Chang Zhang2,3, Xiyi Lu1

  • 1Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.

Nature communications
|February 26, 2025
PubMed
概括

科学家们发现了一种新的致癌性长非编码RNA (lncRNA),ZNF252P,通过蛋白相分离激活c-Myc致癌基因来驱动癌症. 这个ZNF252P/c-Myc轴为癌症治疗提供了一个潜在的新目标.

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