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饮食中的蛋白质摄入量和胃癌,来自病例控制研究的见解
Ngoan Tran Le1,2, Tai Van Nguyen3, Linh Thuy Le4
1Institute of Research and Development, Duy Tan University, Da Nang City, Vietnam. letranngoan@duytan.edu.vn.
Scientific reports
|February 26, 2025
概括
来自全食的高蛋白摄入量与胃癌 (SC) 的风险降低有关. 这种保护作用在越南人群中观察到各种蛋白质来源和人口群体.
科学领域:
- 流行病学 流行病学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 饮食中的蛋白质与胃癌 (SC) 风险之间的关系尚未完全理解.
- 之前的研究已经产生了关于蛋白质摄入量和SC发展的有争议的发现.
研究的目的:
- 调查从全食中摄入的蛋白质与患胃癌 (SC) 的风险之间的关联.
- 研究越南人口中的这种关系,考虑各种蛋白质来源和人口因素.
主要方法:
- 在越南河内进行了一项病例控制研究,涉及1182例SC病例和2995例对照.
- 蛋白质摄入量是使用经过验证的半定量性食物频率问卷来评估的.
- 统计分析利用几率比率 (OR) 和95%置信区间 (95%CI) 来评估SC风险.
主要成果:
- 总体而言,高蛋白摄入量与SC风险降低显著相关 (OR:0.41;95%CI:0.32,0.51).
- 观察到一个一致的剂量反应关系,增加蛋白质摄入量与较低的SC风险相关.
- 对来自动物 (哺乳动物) 和鱼/家禽来源的蛋白质都注意到了有益影响,这种关联在各种子组中持续存在.
结论:
- 高蛋白饮食,特别是来自全食来源的饮食,似乎与越南人口的胃癌风险相反相关.
- 建议进行进一步的研究,以阐明蛋白质摄入对抗胃癌的保护作用背后的机制.
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