在非心脏手术中的手术内低血压和术后风险:元分析
Guanchao Qin1, Ming-Cheng Du1, Ke-Xin Yi1
1Institute of Anesthesiology and Critical Care Medicine, Three Gorges University & Yichang Central People's Hospital, 443000, Yichang, Hubei, People's Republic of China.
BMC anesthesiology
|February 26, 2025
概括
这次元分析发现,中度和高平均动脉压管理策略之间的术后并发症没有显著差异. 最佳的手术内低血压管理仍然是需要进一步研究的领域.
科学领域:
- 麻醉学和重症监护医学
- 手术结果研究研究.
背景情况:
- 术内低血压与术后并发症有关,但最佳管理策略仍在争论中.
- 确定手术内低血压的治疗值对于患者的治疗结果至关重要.
- 这项研究解决了围绕手术内低血压管理的争议.
研究的目的:
- 为了比较术后并发症的发生率,使用不同治疗值来对待手术内低血压.
- 评估平均动脉压管理对患者结局的影响.
- 综合来自随机对照试验的低血压管理的证据.
主要方法:
- 2014-2024年间发表的随机对照试验 (RCT) 的元分析.
- 搜索了PubMed,Cochrane数据库和Embase的相关研究.
- 包括非心脏,非产科手术的RCT,比较低血压治疗值 (低,中等,高MAP).
- 主要结局:术后并发症 (如急性损伤);次要结局:住院时间长度,所有原因的死亡率.
主要成果:
- 八个具有9108名参与者的RCT被纳入了元分析.
- 在中度和高平均动脉压 (MAP) 治疗值之间,没有发现术后并发症的显著差异.
- 住院时间在中度和高MAP组之间没有显著差异.
结论:
- 目前的证据表明,中度和高MAP管理之间的术后并发症没有显著差异.
- 需要进一步的研究来分析手术内低血压的较低治疗值.
- 优化手术内低血压管理需要持续调查.
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