在纤维肌痛的过敏并发症.
Eli Magen1, Eugene Merzon1, Ilan Green1
1From the Division of Research and Innovation, Leumit Health Services, Tel Aviv, Israel.
Allergy and asthma proceedings
|February 26, 2025
概括
与对照组相比,纤维肌痛 (FM) 患者的过敏性疾病,包括喘,鼻炎和皮肤过敏症的发病率显著增加. 这表明在FM管理中需要进行过敏查.
科学领域:
- 类风湿病学 类风湿病学
- 过敏学 过敏学
- 流行病学 流行病学
背景情况:
- 纤维肌痛 (FM) 和过敏状况之间的联系尚未得到充分证实.
- 新出现的证据表明,FM和过敏之间存在潜在的关联.
研究的目的:
- 为了确定被诊断为纤维肌痛的患者中过敏性疾病的患病率.
- 为了比较 FM 患者的过敏并发症率与匹配的对照组.
主要方法:
- 追溯性,基于人口的病例控制研究.
- 使用国际疾病分类,第九次修订 (ICD-9) 代码进行诊断识别.
- 包括 15,869 个 FM 患者和 79,345 个来自 Leumit 健康服务的匹配对照.
主要成果:
- 纤维肌痛患者患上支气管喘 (OR 1.91),过敏性鼻炎 (OR 1.60-1.30) 和慢性鼻炎 (OR 2.46) 的几率更高.
- 在FM组中观察到过敏性结膜炎 (OR 2.05),皮肤炎 (OR 1.48-1.41),疹和慢性的患病率增加.
- 在纤维肌痛患者中,食物过敏 (过敏反应的OR为2.50) 和药物过敏的发病率较高.
结论:
- 纤维肌痛明显与各种过敏性疾病的患病率增加有关.
- 这些发现表明,在纤维肌痛患者的管理中,需要进行常规的过敏学评估.
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