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Updated: May 25, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Published on: March 10, 2018

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通过异构化通过S1P1对CXCR4功能的调节

Hyun-Tae Kim1, Jae-Yeon Jeong2, Won-Ki Huh3,4,5

  • 1School of Biological Sciences, Seoul National University, Seoul, 08826, Republic of Korea.

Cell communication and signaling : CCS
|February 26, 2025
PubMed
概括

这项研究表明,基-1-酸盐受体1型 (S1P1) 与C-X-C化学因子受体4型 (CXCR4) 形成复合体,独特调节CXCR4信号. 这些CXCR4-S1P1异构体通过改变受体功能来影响免疫细胞贩运.

关键词:
在CXCR4中,CXCR4是CXCR4.G蛋白结合受体的受体是G蛋白结合受体的受体.这种异构体是异构体.在S1P1中,S1P1是什么?

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