在血管接入创建中的范式转变研究协议:VAC研究
Hou Guocun1,2, Mi Lanhua1, Bian Fan3
1Department of Vascular Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
The journal of vascular access
|February 27, 2025
概括
修改后的雷达技术用于放射性脑的创建显示出有希望. 这项研究将其临床结果与传统技术在大型随机试验中进行比较.
科学领域:
- 血管外科 血管外科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床试验 临床试验
背景情况:
- 传统的辐射动脉偏差和再植入 (RADAR) 技术使用端到端的动脉到静脉配置.
- 已经开发出一种改进的RADAR (M-RADAR) 技术,其特点是侧向侧解剖并绑定远端脑静脉.
- VAC研究是一项多中心随机对照试验,将M-RADAR与放射性脑形成的常规技术进行比较.
研究的目的:
- 为了比较使用修改RADAR (M-RADAR) 技术与常规技术 (CT) 创建的放射性脑型动脉静脉 (AVF) 的临床结果.
- 为临床医生提供关于AVF手术期间最佳脑静脉治疗策略的明确指导.
主要方法:
- 展望性,多中心,随机研究于2024年12月启动,正在进行参与者招聘.
- 通过纸质案例报告表格 (CRF) 收集数据.
- 据估计,将从中国各地约29个透析单位招募408名参与者.
主要成果:
- 主要终点:AVF的1年初级通透率和静脉旁静脉狭窄的发生率.
- 二级终点: 一年访问辅助初级通透性,访问累积通透性,住院率,死亡率和经济成本分析.
- 该研究目前处于招聘阶段,目前还没有结果.
结论:
- 一个高质量的,充足的动力多中心随机对照试验是必要的.
- 这项试验的目的是为选择放射性脑性AVF的最佳外科手术技术提供最终证据.
相关概念视频
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Development of Blood Vessels
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...


