发现安全的COX-2抑制剂:通过平衡的COX抑制来实现减少结肠炎副作用

Xinlin Zhu1, Qin Li2, Junhui Wu3

  • 1Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.

ChemMedChem
|February 27, 2025
PubMed
概括

研究人员开发了一种新的,平衡的循环氧化酶-2 (COX-2) 抑制剂,化合物21u2009d,显示出强大的抗炎作用. 这种新的候选药物有效地减少了急性结肠炎模型中的损伤,为治疗炎症提供了更安全的替代方案.

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