利多卡因与上腺素注射用于蜂大局部反应
Keith A Denkler1, Rosalind F Hudson2
1Division of Plastic Surgery, University of California, San Francisco, California, USA.
Journal of the American College of Emergency Physicians open
|February 27, 2025
概括
大规模的局部蜂刺反应,导致胀和发红,可以通过利多卡因和上腺素注射快速治疗. 这种创新方法可以立即缓解疼痛,并减少过敏性胀,与传统方法不同.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 皮肤病学 皮肤病学
- 紧急医疗 紧急医疗
背景情况:
- 蜂造成的大型局部反应 (LLR) 影响5-15%的人,呈现为明显的皮肤反应,包括,红血和.
- 目前的治疗方法,如NSAID,抗组胺剂和皮质类固醇,不能立即缓解症状或阻止过敏级联.
- 需要采取快速干预措施,解决疼痛和蜂刺的潜在过敏和炎症反应.
研究的目的:
- 评估皮下和皮内利多卡因与上腺素的疗效,以快速逆转大型本地蜂反应.
- 评估这种治疗对疼痛,胀和过敏反应的直接和短期影响.
- 为了确定上腺素是否可以终止由蜜蜂毒液启动的过敏级联.
主要方法:
- 一个案例研究涉及一个患有外轨道大局部蜂反应的患者.
- 将1%的利多卡因与上腺素通过皮下和皮内注射到刺痛区域.
- 临床观察和记录症状的逆转,包括疼痛,压力和.
主要成果:
- 在注射利多卡因后,疼痛和压力症状的快速和显著逆转.
- 在上腺素给药后2小时内显著减少眼周和眼的胀.
- 没有进一步的症状演变,表明过敏级联被终止.
结论:
- 皮下和皮内利多卡因与上腺素提供快速的症状缓解大局部蜂反应.
- 上腺素的血管收缩和潜在的抗过敏性质可以有效地阻止炎症级联.
- 这种注射技术为严重的蜜蜂刺反应,特别是周围轨道刺反应提供了一个有希望的,即时的治疗选择.
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