使用诊断代码定义与年龄相关的黄斑退化症队列的变化
Fritz Gerald Paguiligan Kalaw1,2, Jimmy S Chen1,2, Sally L Baxter1,2
1Division of Ophthalmology Informatics and Data Science, Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, 9415 Campus Point Dr MC0946, La Jolla, CA 92093, USA.
Informatics (MDPI)
|February 27, 2025
概括
确定与年龄相关的黄斑变性 (AMD) 研究的患者队列有很大的差异. 不一致使用国际疾病分类 (ICD) 代码导致研究中AMD患者的表现不准确.
科学领域:
- 眼科医生 眼科 眼科
- 医疗信息学 医疗信息学
- 生物统计学 生物统计学
背景情况:
- 电子健康记录 (EHR) 的二次分析对研究至关重要.
- 与年龄相关的黄斑变性 (AMD) 是导致失明的主要原因.
- 缺乏标准化方法来识别EHR数据中的AMD患者队列.
研究的目的:
- 调查国际疾病分类 (ICD) 代码使用的变化,以定义与年龄相关的黄斑变性 (AMD) 患者队列.
- 评估出版文献中AMD队列定义的准确性和完整性.
主要方法:
- 对37篇研究AMD的文章进行了系统审查.
- 分析出版年份,数据集来源,受试者数和使用的ICD代码 (ICD-9,ICD-9-CM,ICD-10,ICD-10-CM).
- 评估队列定义的准确性,完整性和与AMD相关性的评估.
主要成果:
- 在ICD代码用于AMD队列识别方面存在实质性的差异.
- 使用ICD-10代码的研究表明,与ICD-9/9-CM (7%) 相比,ICD-10代码的准确性更高 (78%).
- 72%的队列定义有不完整或缺失的AMD代码,35%包括无关代码.
结论:
- 目前使用ICD代码定义AMD患者队列的方法不一致,经常不准确.
- 标准化ICD代码的使用对于可重现的研究和可靠的AMD队列识别至关重要.
- 在眼科研究中对二次EHR数据分析需要改进数据协调.
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