睡眠时间型对血压和代谢标志物的影响
Weiwei Huang1, Qinglu Wang2, Yuan Gao3
1Department of Neurology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China.
Frontiers in neurology
|February 27, 2025
概括
晚上睡眠类型显示血压降低和代谢标记的改变. 这突显了睡眠时刻型对健康的影响,特别是关于心血管调节和代谢健康.
科学领域:
- 睡眠科学 睡眠科学
- 代谢健康 代谢健康
- 时间生物学 时间生物学
背景情况:
- 睡眠时刻型,一个人对早上或晚上活动的自然倾向,显著影响生理过程.
- 了解睡眠模式和代谢健康之间的联系对于公共卫生倡议至关重要.
研究的目的:
- 为了研究睡眠时间型和各种代谢标志物之间的相关性.
- 阐明不同睡眠时间型对人类健康的影响,重点关注代谢参数和血压.
主要方法:
- 对442名成年志愿者 (年龄在23-70岁) 进行了早上晚上问卷调查 (MEQ).
- 参与者被分为早晨,中午和晚上的时间类型.
- 收集血压测量和禁食血液样本进行全面的生物化学分析,包括肝脏和功能,葡萄糖和脂质资料.
主要成果:
- 时间型之间存在显著的年龄差异 (p < 0.01),但不是性别,身高,体重或BMI.
- 经过年龄调整后,晚上类型的患者表现出较低的肌素和酸氨基转移酶水平,与其他组相比 (p < 0.05).
- 晚间的时刻型与较低的缩血压,腹缩血压和平均动脉压 (MAP) (p <0.05) 相关.
- MEQ得分与静缩血压,静缩血压和MAP正相关 (r = 0.0990.104,p < 0.05).
结论:
- 晚上的睡眠类型更容易受到白天的嗜睡.
- 在睡眠时间类型中观察到血压的显著变化 (静脉压,静脉压,MAP).
- 这些血压差异可能源于睡眠时间型对自主调节或昼夜节律的影响.
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