使用定制的ChatGPT-4进行OTC药物的药物咨询:与ChatGPT-3.5和ChatGPT-4o进行比较
Keisuke Kiyomiya1, Tohru Aomori2, Hisakazu Ohtani1,3,4
1Division of Clinical Pharmacy, Keio University Faculty of Pharmacy, Minato-ku, Tokyo, Japan.
Digital health
|February 27, 2025
概括
将生成AI与药物信息进行定制,可以显著提高其对非处方药物指导的准确性,为消费者提供一种有价值的工具,并可能有助于临床药房实践.
科学领域:
- 医疗保健中的人工智能
- 消费者健康信息消费者健康信息
- 药理学和药物信息
背景情况:
- 在日本,消费者经常在没有咨询药剂师的情况下获得非处方药 (OTC) 药物.
- 生成型人工智能 (AI) 越来越受欢迎,这引发了关于其在消费者药物咨询中的使用的问题.
- 之前的研究表明,ChatGPT-3.5在提供基于包装插件的药物指导方面准确度低 (20.8%).
研究的目的:
- 为了比较定制生成AI模型与最新的非定制版本 (ChatGPT-4o) 和前一个版本 (ChatGPT-3.5) 的性能,用于药物指导.
- 评估定制和版本更新对AI性能在提供准确可靠的药物信息方面的影响.
- 评估定制AI作为临床药房和消费者药物支持工具的潜在有用性.
主要方法:
- 通过提供日语说明和上传22种OTC药物的包装插件数据,创建了一个定制版本的ChatGPT-4.
- 在之前的研究中使用的同样的264个与药物有关的问题被提出给定制的ChatGPT-4,ChatGPT-4o和ChatGPT-3.5.5.
- 绩效的评估是基于AI生成的响应与包装插入说明的准确性,相关性和可靠性.
主要成果:
- 定制的ChatGPT-4获得了高分:93.2%的准确性,100%的相关性和60.2%的可靠性.
- 56.1%的自定义ChatGPT-4的响应符合所有三个标准,比ChatGPT-3.5 (2.7倍增加) 和ChatGPT-4o (1.3倍增加) 显著改善.
- 性能,特别是涉及药品品牌名称的问题,通过定制的人工智能模型显著提高.
结论:
- 将生成AI与特定药物信息 (如包装插件) 进行定制,可以大大提高药物指导的准确性和可靠性.
- 定制的GPT模型与以前和最新的非定制AI版本相比,表现出卓越的性能.
- 这种定制的人工智能方法具有很大的潜力,可以成为临床药房中一个有价值的工具,为消费者增强药物咨询.
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