转移性形腺瘤:一个罕见的实体
Amar Hazwan Zainal Ariffin1, Sai Guan Lum2,1, Ng Chong Sian3
1Department of Otorhinolaryngology - Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Cureus
|February 27, 2025
概括
转移性多形腺瘤 (MPA) 是多形腺瘤 (PA) 的罕见并发症. 早期检测和完整的外科切除对于管理MPA至关重要,因为其他治疗方法是无效的,生存率低.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 手术瘤学手术瘤学
背景情况:
- 转移性多形腺瘤 (MPA) 是一种罕见但具有攻击性的长期多形腺瘤 (PA) 的结果.
- 对MPA的患病率和风险因素,包括早期发病和复发的PA,需要进一步了解.
- 由于MPA的死亡率很高,因此需要有效的诊断和管理策略.
研究的目的:
- 为了突出转移性多形腺瘤的罕见性和临床特征.
- 强调早期检测和MPA的适当外科治疗的重要性.
- 报告一个复发的腺PA病例与ipsilateral淋巴结转移.
主要方法:
- 对转移性多形腺瘤现有文献的综述.
- 临床病例介绍一个患有复发性腺PA和转移的患者.
- 讨论MPA的诊断和治疗方式.
主要成果:
- 转移性形腺瘤与显著的发病率和死亡率有关.
- 复发的多形腺瘤需要高度怀疑转移.
- 完整的外科切除是主要的治疗方法,尽管复发和转移仍然可能发生.
结论:
- 转移性形腺瘤是一种罕见但严重的疾病,需要谨慎监测和积极管理.
- 整体外科切除,如胸膜切除术,是MPA的首选治疗方法.
- 尽管有治疗方法,MPA的预后不好,死亡率高.
相关概念视频
Metastasis
5.5K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.5K
Abnormal Proliferation
4.4K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.4K
Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K


