麻症症状和饮食模式与肺癌风险的关系:一项前性队列研究
Huijun Zhou1, Fubin Liu1, Jingyi Xu2
1Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology, Key Laboratory of Prevention and Control of Major Diseases in the Population, Ministry of Education, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, 300060, China. songfangfang@tmu.edu.cn.
Food & function
|February 27, 2025
概括
萨科佩尼亚症状增加了肺癌的风险,特别是在年轻人中. 富含全谷物的饮食可以减轻这些风险,并改善那些手握强度低的人的结果.
科学领域:
- 老年病学和瘤学
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 有限的研究存在于sarcopenia对肺癌在一般人群的影响.
- 营养干预措施可能提供一种治疗萨科佩尼亚的策略.
- 这项研究探讨了sarcopenia症状,饮食模式,以及它们对肺癌风险的综合影响.
研究的目的:
- 检查萨科佩尼亚症状与肺癌发病率和死亡率之间的关联.
- 为了确定饮食模式是否会改变与肉症相关的肺癌风险.
- 探索萨科佩尼亚症状和饮食模式对肺癌结局的联合影响.
主要方法:
- 来自英国生物银行的361,763名参与者的前性队列研究.
- 使用欧洲老年人肉症工作组2 (EWGSOP2) 标准评估的肉症症状.
- 通过主要成分分析确定的饮食模式;用于分析的Cox比例危险模型.
主要成果:
- 萨科佩尼亚症状与肺癌发病率和死亡率的增加有关,特别是在60岁以下的人群中.
- 缓慢的步行节奏与更高的肺癌发病率 (HR: 1.49) 和死亡率 (HR: 1.54) 有着显著的关联.
- 较高的全谷物饮食模式的坚持减少了肺癌发病率 (HR:0.71) 和死亡率 (HR:0.68);这种效应也观察到手握强度低.
结论:
- 麻症的症状与肺癌风险和死亡率的增加有关,即使在年轻人群中也是如此.
- 富含全谷物食物的饮食可能有助于改善肉症的症状,并降低肺癌的风险.
- 饮食干预措施,特别是全谷物,在管理与肉症相关的肺癌风险方面表现有前途.
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