完成肠道日记和教育对便失禁严重性的影响
Uduak U Andy1, Benjamin Carper2, Halina Zyczynski3
1From the Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA.
4周的运行期,包括肠道日记和教育,并没有显著改变女性便失禁 (FI) 症状的严重程度. 大多数参与者仍然有资格参加试验,这表明启动阶段的影响最小.
科学领域:
- 胃肠病学 胃肠病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 临床试验 临床试验
背景情况:
- 便失禁 (FI) 是一种影响生活质量的常见疾病.
- 临床试验中经常使用运行期来稳定症状并确保患者的资格.
- 在FI试验中,运行期对症状严重性的影响需要进一步调查.
研究的目的:
- 为了评估4周的运行期对便失禁症状严重性的影响.
- 为了评估症状严重程度的变化 (圣马克 (Vaizey) 评分) 和在开始期内每周FI的发作.
- 为了确定在试行期后成为不符合试验资格的参与者的比例.
主要方法:
- 一个随机对照试验的二次分析,涉及FI的女性.
- 参与者接受了为期4周的试行期,其中包括FI教育和肠道日记的完成.
- 使用圣马克 (Vaizey) 评分和第1周和第4周的每周FI情节来测量症状严重程度.
主要成果:
- 圣马克 (Vaizey) 的得分从第1周到第4周没有显著变化 (平均变化-0.93).
- 在开始期内,每周便失禁事件和其他肠道日记指标保持稳定.
- 只有6%的女性 (11在185人中) 成为不合格的,具有较低的基线症状得分.
结论:
- 与教育和肠道日记相结合的4周运行期不会显著改变FI妇女的症状严重程度.
- 运行期对这种不耐火的人群的资格影响很小.
- 研究结果表明,在某些FI患者群体中,运行期可能对症状稳定有有限的影响.
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