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Updated: May 25, 2025

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对MEK1/2抑制剂的综合计算和实验洞察:结构验证,对接,ADMET,分子动力学和抗癌评估

Rohit Pal1, Gurubasavaraja Swamy Purawarga Matada2, Ghanshyam Teli3

  • 1Acharya and BM Reddy College of Pharmacy, Pharmaceutical Chemistry, Acharya and BM Reddy college of pharmacy, 560090, Bengaluru, INDIA.

Chemistry & biodiversity
|February 27, 2025
PubMed
概括

这项研究确定RO5126766是癌症治疗中强大的MEK1/2抑制剂. 计算和体外分析证实了它对攻击性和耐治疗性癌症的有效性.

关键词:
作为MEK抑制剂的使用.分子动力学分子动力学结合能量是一种约束能量.停靠研究对接研究一个口袋绑定绑定.

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