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患有COVID-19后急性后果的人体内皮质功能受损:综合运动训练训练的影响

Tae Gu Choi¹, Jae Yeop Kim, Joon Youp Seong

¹Author Affiliations: Department of Sport Science, University of Seoul, Seoul, Republic of Korea (Mrs Choi, J.Y. Kim, Seong, Jung and Y.W. Kim, Ms Min, and Drs Cho, H.J. Kim, and Jae); Diabetes Research Centre, Real World Evidence Unit, Leicester General Hospital, University of Leicester, Leicester, UK (Dr Kunutsor); Section of Cardiology, Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Saint Boniface Hospital, Winnipeg, Canada (Dr Kunutsor); Graduate Program of Movement Science and Education, Columbia University, New York, NY, USA (Dr Heffernan); and Graduate School of Urban Public Health, University of Seoul, Seoul, Republic of Korea (Dr Jae).

Journal of cardiopulmonary rehabilitation and prevention

|February 27, 2025

概括

冠状病毒疾病-2019 (PASC) 后急性后果与内皮功能受损有关. 联合运动训练有效地恢复PASC患者的血管功能,提供了一个有前途的干预措施.

科学领域:

心血管生理学心血管生理学
肺部康复肺部康复
传染病研究传染病研究

背景情况:

冠状病毒疾病-2019 (PASC) 后急性后果可以表现为各种长期健康问题.
内皮功能障碍越来越多地被认为是PASC症状的潜在贡献者.
了解PASC对血管健康的影响对于开发有效的治疗方法至关重要.

研究的目的:

为了比较PASC患者和健康对照者的内皮功能.
评估联合运动训练计划在改善PASC患者内皮功能方面的有效性.

主要方法:

一项横截面研究比较了PASC患者和健康个体的内皮功能 (流介导扩张).
一项为期8周的干预研究评估了联合有氧,抵抗和鼓舞肌肉训练对PASC患者内皮功能,VO2峰值,呼吸障碍和疲劳的影响.
在两种研究设计中都使用了对照组进行比较.

主要成果:

与健康对照人群相比,患有PASC的个体表现出显著受损的内皮功能.
8周的综合运动训练计划显著改善了PASC患者的内皮功能,使其恢复到与健康个体相似的水平.
运动干预也导致氧气吸收峰值 (VO2峰值) 的显著改善,呼吸障碍和疲劳的减少.

结论:

帕斯克与显著的内皮功能障碍有关.
联合炼训练代表了一种可行的和有效的干预措施,以恢复患有PASC的个体的血管功能.
这种多式运动方法有望改善PASC患者的整体心血管健康和生活质量.

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