在斯洛文尼亚,扩散性异常性骨超静止症的患病率和与冠状动脉结石化相关的情况
Vesna Lesjak1, Timea Hebar1, Maja Pirnat1,2
11Radiology Department, University Medical Centre Maribor, Maribor, Slovenia.
Radiology and oncology
|February 27, 2025
概括
扩散性异常性骨高静止症 (DISH) 影响7.8%的患者. 虽然DISH在初步分析中与BMI和糖尿病等因素有关,但在本研究中,DISH与冠状动脉结 (CAC) 没有独立联系.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 扩散性异常性骨高静止症 (DISH) 是一种影响脊柱的疾病.
- 心脂肪组织 (EAT) 密度和冠状动脉结 (CAC) 是心血管风险的标志物.
- 了解DISH和心血管参数之间的关系至关重要.
研究的目的:
- 分析斯洛文尼亚DISH的流行病学.
- 评估EAT密度,CAC和DISH之间的关联.
- 确定影响EAT密度和CAC的因素,在患有DISH和没有DISH的患者中.
主要方法:
- 对219名接受冠状动脉CT血管造影 (CCTA) 的患者的回顾性分析.
- 使用非对比成像对DISH,CAC得分和EAT减弱的量化.
- 相关性和多变量回归分析以探索关联.
主要成果:
- DISH 的流行率为 7.8%.
- 单变量分析显示DISH和BMI,年龄和糖尿病之间的关联,在多变量分析中没有持续.
- 性别,年龄,高血压和EAT衰减与增加CAC层相关,但DISH与CAC没有独立联系.
结论:
- 研究队列中DISH的流行程度与现有文献一致.
- 在DISH和冠状动脉化的程度之间没有发现独立的关系.
- 这些发现表明,DISH和冠状动脉疾病之间存在复杂的,潜在的非因果关系.
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