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口服生物可用和局部选择性共价性刺痛抑制剂,来自于宏环海洋二甲类基

Guang-Hao Niu1, Wan-Chi Hsiao2,3, Po-Hsun Lee2,3

  • 1Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Miaoli 35053, Taiwan.

Journal of medicinal chemistry
|February 27, 2025
PubMed
概括

一种新的药物GHN105,是一种口服可用的共价性STING抑制剂,有效地阻断cGAS-STING先天免疫通路. 这一发展为炎症性疾病提供了一个有前途的治疗策略.

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