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Updated: May 25, 2025

Xenopus laevis as a Model to Identify Translation Impairment
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Published on: September 27, 2015

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在大肠杆菌中体内翻译的机制建模可靠地识别了适应良好的和优化的RNA序列

Jan Spindler1, Christina Giakissiklis1, Catharina Stierle1

  • 1Institute of Biochemical Engineering, University of Stuttgart, Stuttgart 70569, Germany.

ACS synthetic biology
|February 27, 2025
PubMed
概括

这项研究引入了翻译延长的新模型,揭示了除了编码子使用之外的因素对大肠杆菌的基因表达效率有重大影响. 该模型预测异质基因的翻译率降低,突出显示了改善蛋白质生产的区域.

关键词:
在的中.在活体中合成蛋白质合成数学模型是一个数学模型.建模 建模模型 建模模型核糖体是核糖体中的一个.转录和翻译 转录和翻译

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