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Updated: May 25, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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预测,一个由分类器策划的AlphaFold建模的蛋白质-蛋白质相互作用数据库

Ernst W Schmid1, Johannes C Walter2

  • 1Department of Biological Chemistry & Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.

Molecular cell
|February 27, 2025
PubMed
概括

我们开发了一种机器学习分类器 (SPOC),以准确识别由AlphaFold-Multimer预测的真正的蛋白质-蛋白质相互作用 (PPI). 这种工具提高了大型结构互原子研究的可靠性.

关键词:
在 AF-M 数据库中.在AF-M中获得得分.阿尔法折叠多元化器在PPI数据库中,可以找到PPI数据库.这是一个PPI屏幕.SPOCOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC SPOC基因组维护是基因组的维护.在化物中的相互作用屏幕.预测未来的情况蛋白质与蛋白质的相互作用

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