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因子抑制剂测试:来自澳大利亚/亚太地区的更新

Emmanuel J Favaloro1,2,3, Sandya Arunachalam4

  • 1Department of Haematology, Sydney Centres for Thrombosis and Haemostasis, Institute of Clinical Pathology and Medical Research (ICPMR), Westmead Hospital, Westmead, NSW, Australia.

Seminars in thrombosis and hemostasis
|February 27, 2025
PubMed
概括

第八因子 (FVIII) 抑制剂测试在检测抑制剂方面具有很高的准确性,超过99%的结果正确识别了它们的存在或不存在. 大多数错误来自数据输入,而不是分析问题.

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In Vitro Drug Release Testing: Overview, Development and Validation01:10

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In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...