环保 持续释放 抗真菌 循环素 包含 复杂的纳米纤维用于控制真菌
Fengrui Li1, Yue Xiu1, Anqi Wang1
1Department of Chemistry, Northeast Agricultural University, Harbin 150030, China.
Langmuir : the ACS journal of surfaces and colloids
|February 27, 2025
概括
研究人员使用环极素 (CD) 封装开发了新的二元形 (DIM) 纳米纤维. 这些增强的农药输送系统提高了水溶性,控制释放,并提高了对植物病原体的抗真菌活性.
科学领域:
- 农业科学 农业科学
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
背景情况:
- 疏水性农药配方面临着制造方面的挑战和环境风险.
- 作为一种关键的杀菌剂,Dimethomorph (DIM) 具有较差的水溶性和对非标生物的潜在危害.
- 现有的农药输送方法通常依赖于有机溶剂和表面活性剂,限制了它们的可持续性.
研究的目的:
- 为了增强水溶性和控制释放的二度形态 (DIM).
- 开发一种新的农药输送平台,使用环氧 (CD) 纳米纤维的复杂纳米纤维.
- 提高DIM对植物病原体的抗真菌功效,同时尽量减少对环境的影响.
主要方法:
- 在循环德克斯特林 (CD) 腔内封装二元形态 (DIM) 以形成包容复合体.
- 通过电制造DIM/CD纳入复合物成无珠,光滑的纳米纤维.
- 纳米纤维形态的表征,DIM释放动力学,以及对*Rhizoctonia solani*和*Haematonectria hematococco**的抗真菌活性.
主要成果:
- 纳米纤维的DIM/CD纳入复合物表现出最佳的水溶性和持续的DIM释放,达到约75%的累积释放平原.
- 制造的纳米纤维显示出由于CD的空间限制效应,增强了热稳定性.
- 与自由DIM相比,DIM/CD纳入复杂纳米纤维的抗真菌活性显著更高,在144小时内对*Rhizoctonia solani*的抑制率为55.8% (DIM/HPβCD) 和53.6% (DIM/HPγCD).
结论:
- 纳米纤维含有环氧德克斯的复杂纳米纤维提供了一个可行的和有效的平台,用于持续提供像DIM这样的疏水性农药.
- 这种方法增强了抗真菌生物活性,减少了所需的农药喷频率,并减轻了对非目标生物的风险.
- 开发的纳米纤维代表了可持续农业和改进的作物保护战略的有希望的进步.
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