在BPH手术治疗后扩大LUTS药物使用:美国医疗保健索赔分析
Steven Kaplan1, Ronald P Kaufman2, Dean Elterman3
1Icahn School of Medicine at Mount Sinai, Department of Urology, Mount Sinai, New York, NY, USA. Steven.Kaplan@MountSinai.org.
Prostate cancer and prostatic diseases
|February 27, 2025
概括
良性前列腺增生 (BPH) 手术患者经常在手术后继续服用药物. 在TURP,PVP或PUL手术5年后,大约10%的男性需要BPH药物,这表明无论手术方法如何,都需要持续的医疗需求.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗保健服务研究 医疗服务研究
- 药物经济学 药物经济学
背景情况:
- 在良性前列腺增生 (BPH) 手术后术后使用药物的研究不足.
- 了解BPH手术后的药物需求对于患者管理至关重要.
- 本研究检查了BPH常见手术干预后的药物需求.
研究的目的:
- 为了比较术后的药物使用后,通过尿道切除前列腺 (TURP),GreenLight激光光蒸发 (PVP),和前列腺尿道提升 (PUL).
- 为了评估持续和新的医疗治疗的实际情况,使用BPH后手术.
主要方法:
- 分析了一大批美国医疗保险和商业保险索赔数据集.
- 包括具有TURP,PVP或PUL后至少一年的随访数据的患者.
- 将手术声明与药品声明联系起来,以追踪α阻断剂,5α减小酶抑制剂或组合疗法使用.
主要成果:
- 36,629名BPH男性接受了门诊的TURP,PVP或PUL治疗.
- 术后一年的医疗治疗使用率是PUL (4.1%) 与 TURP (6.2%) 和 PVP (6.6%) 相比最低.
- 五年后的术后医疗使用在所有手术中都是相似的:TURP (10.6%),PVP (10.4%) 和PUL (10.3%).
结论:
- 很大一部分BPH患者在手术后5年需要药物治疗.
- 在5年后,术后药物使用在TURP,PVP和PUL手术中保持一致.
- 这些发现凸显了手术干预后BPH患者的长期医疗管理需求.
相关概念视频
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:21Drugs for Treatment of Constipation-Predominant IBS
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
01:25Urinary Tract Calculi VI: Surgical Management
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...