探索静坐行为对缺乏症的非线性关联和值效应
Liangchun Cai1, Haiping Xie2, Wue Li3,4
1Department of Endocrinology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China. cailiangchunfj@163.com.
Endocrine
|February 27, 2025
概括
长时间的久坐行为与成人男性缺乏症 (TD) 的风险增加有关. 这种关联在每天静坐时间超过4.5小时时变得更加明显.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 男人的健康 男人的健康
背景情况:
- 久坐不动行为是一个日益严重的公共卫生问题.
- 它与激素失衡的联系,例如缺乏症 (TD),需要进一步调查.
- 了解这种关联对于预防性健康策略至关重要.
研究的目的:
- 在成年男性中调查久坐时间和丸激素缺乏之间的关联.
- 探索这种关联中潜在的非线性关系和值.
- 为了确定高风险的特定人群.
主要方法:
- 从2011-2016年NHANES中对6057名成年男性进行横截面分析.
- 静坐时间分为四分位数;TD定义为血清丸激素<300 ng/dL.
- 进行了后勤回归,受限立方线和子组分析.
主要成果:
- 在久坐时间和TD之间发现了显著的积极关联.
- 观察到非线性关系,每天静坐时间超过4.5小时,TD风险增加.
- 非西班牙裔白人,吸烟者和饮酒者中协会最强;糖尿病患者中较弱.
结论:
- 长时间的久坐行为与较高的缺乏症风险显著相关.
- 久坐不动的行为可能是TD发展的关键因素,特别是在风险群体中.
- 研究结果强调了减少久坐时间对男性荷尔蒙健康的重要性.
相关概念视频
Testosterone: Functions and Regulation
514
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
514
Disorders of the Male Reproductive System
289
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
289
Regression Toward the Mean
6.3K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.3K
Relationship Formation
39.6K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
39.6K


