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Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
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除了出血: 导航胎儿腹腔内出血
Hillary C Lee1, Amee A Amin1, Danielle N Gonzales1
1Section of Neonatal-Perinatal Medicine, Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.
Journal of neonatal-perinatal medicine
|February 28, 2025
概括
产前腹腔内出血 (IVH) 往往导致不良结果. 然而,这个案例显示,一个健康的婴儿与IV级IVH和遗传综合征达到正常的发展里程碑在六个月.
科学领域:
- 新生儿神经学 新生儿神经学
- 胎儿医学 胎儿医学
- 遗传学 是一个遗传学.
背景情况:
- 产前腹腔内出血 (IVH),发生在子宫内,发生率为每10,000例中1-5例.
- 胎儿内出血预后不好,死亡率高达40%,幸存者中只有不到50%的患者经历了正常的神经发育结果.
- 关于产前诊断的内出血的神经发育预后的数据有限.
研究的目的:
- 提出一个健康的产后婴儿与产前诊断的IV级胎儿IVH的病例.
- 要突出神经发育的结果,在一个严重的产前IVH与遗传综合征相关的病例.
- 为了解胎儿内出血的结果做出贡献.
主要方法:
- 在产前诊断出患有单边IV级IVH和双边大脑心室巨变的产后婴儿的病例报告.
- 产后评估包括MRI,感染和血液学评估.
- 基因检测显示15q11.2删除综合征.
主要成果:
- 婴儿在第18天被送回家,可以容忍食,并适当增加体重.
- 序列神经成像显示出出血没有进展.
- 在6个月大时,婴儿已经达到所有发展里程碑.
结论:
- 尽管与胎儿内出血 (ICH) 相关的预后普遍不佳,特别是III或IV级,但可能有良好的结果.
- 遗传因素可能在产前IVH的呈现和结果中发挥作用.
- 这一案例强调了关于胎儿ICH的全面评估和个性化咨询对父母的重要性.
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