喘患者认知障碍的患病率和风险:系统性审查和元分析
Ganesh Bushi1,2, Mahalaqua Nazli Khatib3, Shilpa Gaidhane4
1Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Brain and behavior
|February 28, 2025
概括
喘患者的认知障碍患病率为16.3%. 这种慢性呼吸道疾病与认知能力下降风险增加47%有关,包括痴呆症和阿尔茨海默病.
科学领域:
- 神经学 神经学
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 喘是一种常见的呼吸系统疾病,疑似与认知健康有关.
- 喘和认知功能之间的确切关系尚不清楚.
- 这项研究系统地审查和分析数据,以澄清这种关联.
研究的目的:
- 为了确定喘患者认知障碍的患病率.
- 评估喘患者认知能力下降的风险.
- 综合现有的关于喘和认知健康的研究.
主要方法:
- 在主要数据库 (PubMed,EMBASE,Web of Science) 进行了系统的文献搜索,直到2023年12月.
- 在10项符合条件的研究中,使用随机效应模型进行了元分析.
- 研究质量使用纽卡斯尔-太华尺度进行评估.
主要成果:
- 在喘患者中,认知障碍的综合患病率为16.3%.
- 喘患者的认知障碍风险比率增加了1.47倍.
- 发现喘与认知能力下降,痴呆和阿尔茨海默病风险增加之间存在显著的关联.
结论:
- 喘和更高的认知能力下降风险之间存在着显著的联系,包括痴呆症和阿尔茨海默病.
- 将认知健康评估整合到喘护理中至关重要.
- 需要进一步的研究来了解机制,并开发有针对性的治疗方法.
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